Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.67 |
| ▸ | HRH2 | P25021 | 5/20 | 0.56 |
| ▸ | HRH1 | P35367 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989120 | 0.89 | HRH2 (0.55) | CHRM3HRH2HRH1OPRK1CHRM1 | |
| SCHEMBL4984605 | 0.84 | CHRM1 (0.66) | HRH2HRH1CHRM1 | |
| SCHEMBL18199751 | 0.81 | CHRM3 (1.00) | CHRM3PKMKCNH2 | |
| SCHEMBL3864848 | 0.81 | CHRM3 (0.62) | CHRM3PKMKCNH2DRD3 | |
| SCHEMBL18390259 | 0.79 | CHRM1 (0.61) | CHRM3HRH2HRH1KCNH2DRD3 | |
| Hydrochloric Acid SCHEMBL21995059 | 0.79 | ROCK2 (0.54) | CHRM3HRH2HRH1CHRM1 | |
| Hydrochloric Acid SCHEMBL21995057 | 0.79 | ROCK2 (0.54) | CHRM3HRH2HRH1CHRM1 | |
| SCHEMBL28015716 | 0.77 | CHRM3 (0.58) | CHRM3HRH2HRH1PKMKCNH2 | |
| SCHEMBL9462405 | 0.77 | PKM (0.51) | CHRM3PKMKCNH2DRD3 | |
| SCHEMBL9462114 | 0.77 | PKM (0.51) | CHRM3PKMKCNH2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5032645-A | — | — | None | — | — | JP | disclosed |
| US-5318970-A | Cyclooxygenase, lipoxygenase inhibitors | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0549797-A1 | ISOXAZOLE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND MEDICINAL USE THEREOF | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1993-07-07 | — | — | EP | disclosed |
| JP-H0532645-A | AMINE COMPOUND | TAIHO YAKUHIN KOGYO KK | 1993-02-09 | — | — | JP | disclosed |
| US-5182284-A | Antiasthmatic agent, antiallergen, antiinflammatory agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0465659-A1 | PIPERAZINE COMPOUND, PRODUCTION THEREOF, AND MEDICINAL USE THEREOF | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | disclosed |