SCHEMBL9463149

SCHEMBL9463149

CCOC(=O)C(CCC[Si](C)(OC)OC)C(=O)OCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
L3MBTL1 Q9Y468 6/20 0.42
MAPK1 P28482 4/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.42
POLB P06746 2/20 0.39
MAPT P10636 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
PTPN1 P18031 2/20 0.34
CPB2 Q96IY4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6888022 0.84 L3MBTL1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL15383702 0.83 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL11655565 0.78 TDP1 (0.56) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL7659602 0.78 TDP1 (0.56) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL11035145 0.78 TDP1 (0.46) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL1268292 0.76 TDP1 (0.45) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL6901399 0.76 TDP1 (0.55) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL21073906 0.76 TDP1 (0.55) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL15384765 0.76 L3MBTL1 (0.40) TDP1KMT2AMEN1L3MBTL1MAPK1
SCHEMBL15383691 0.75 TDP1 (0.41) TDP1KMT2AMEN1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5093006-A None JP disclosed
JP-H0593006-A ANIONIC POLYMERIZATION INITIATOR COMPOSED OF COMPOUND HAVING HYDROLYZABLE GROUP BONDED TO SILICON ATOM TOAGOSEI CHEM IND CO LTD 1993-04-16 JP disclosed