SCHEMBL6888022

SCHEMBL6888022

CCOC(=O)C(CCC[Si](OC)(OC)OC)C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.47
TDP1 Q9NUW8 5/20 0.47
MAPK1 P28482 4/20 0.47
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
PTPN1 P18031 1/20 0.35
LMNA P02545 1/20 0.33
CPB2 Q96IY4 1/20 0.33
CTSK P43235 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15384765 0.91 L3MBTL1 (0.40) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL1268292 0.85 TDP1 (0.45) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL9463149 0.84 TDP1 (0.44) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL15383702 0.81 TDP1 (0.47) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL6344840 0.80 LDHA (0.33) TDP1MAPK1KMT2AMEN1LMNA
SCHEMBL11118135 0.80 TDP1 (0.44) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL11655565 0.80 TDP1 (0.56) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL7659602 0.80 TDP1 (0.56) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL11035145 0.79 TDP1 (0.46) L3MBTL1TDP1MAPK1ALDH1A1TSHR
SCHEMBL12471965 0.79 LMNA (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733828-B2 Method of fabricating nanostructured materials NATIONAL TSING HUA UNIVERSITY (TW) 2004-05-11 US claimed
US-20030152759-A1 Method of fabricating nanostructured materials NATIONAL TSING HUA UNIVERSITY (TW) 2003-08-14 US disclosed
US-6251280-B1 A TEMPLATE MOLECULE IS BOUND TO ONE END OF BIFUNCTIONAL LIGANDS TO FORM A COMPLEX PRIOR TO BINDING OF THE BIFUNCTIONAL LIGANDS TO THE SUBSTRATE. UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2001-06-26 US disclosed