Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 5/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813858 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CETPANPEPLAP3L3MBTL1 | |
| SCHEMBL28326266 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CETPANPEPLAP3L3MBTL1 | |
| SCHEMBL3820546 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ANPEPLAP3L3MBTL1 | |
| SCHEMBL28767753 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CETPANPEPLAP3 | |
| SCHEMBL10902569 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CETPANPEPLAP3CA12 | |
| SCHEMBL10902574 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CETPANPEPLAP3 | |
| SCHEMBL4709894 | 0.80 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL3812875 | 0.80 | L3MBTL1 (0.42) | ALDH1A1ANPEPLAP3L3MBTL1 | |
| SCHEMBL29068436 | 0.77 | POLB (0.45) | ALDH1A1ANPEPLAP3L3MBTL1 | |
| SCHEMBL9462930 | 0.77 | L3MBTL1 (0.56) | CETPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208224-A | Phosphorus containing compounds as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |