Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600192 | 0.82 | METAP2 (0.48) | KDM4EGSK3BALDH1A1TSHRHSD17B10 | |
| SCHEMBL3543756 | 0.81 | KDM4E (0.68) | KDM4EGSK3BALDH1A1TSHRHSD17B10 | |
| SCHEMBL30374630 | 0.81 | KDM4E (0.68) | KDM4EGSK3BALDH1A1TSHRHSD17B10 | |
| SCHEMBL7915675 | 0.77 | ALDH1A1 (0.60) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL28595657 | 0.77 | METAP2 (0.44) | KDM4EGSK3BALDH1A1TSHRHSD17B10 | |
| SCHEMBL11632357 | 0.77 | HPGD (0.49) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL29183499 | 0.75 | TSHR (0.55) | KDM4EGSK3BALDH1A1TSHRHSD17B10 | |
| SCHEMBL15459228 | 0.75 | ALDH1A1 (0.75) | KDM4EGSK3BALDH1A1TSHRHSD17B10 | |
| SCHEMBL29051439 | 0.74 | CA12 (0.68) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL6365304 | 0.74 | CA12 (0.57) | KDM4EGSK3BALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5269816-A | Water-soluble reactive triazine dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| US-4087407-A | Process for the production of epoxy silicate foam | BLOUNT DAVID H | 1978-05-02 | — | — | US | disclosed |