Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.96 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | ALPG | P10696 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | NPY1R | P25929 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | NPY2R | P49146 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780224 | 0.98 | NPSR1 (1.00) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL9935641 | 0.86 | NPSR1 (0.72) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL4162470 | 0.85 | ALDH1A1 (0.95) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL29169490 | 0.84 | NPSR1 (0.70) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL10426396 | 0.83 | ALDH1A1 (1.00) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL10060106 | 0.83 | ALDH1A1 (1.00) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL14493538 | 0.83 | ALDH1A1 (1.00) | NPSR1MAPTGAAALDH1A1ALPG | |
| Hydrogen Peroxide SCHEMBL8610678 | 0.83 | ALDH1A1 (0.82) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL27410799 | 0.82 | NPSR1 (0.68) | NPSR1MAPTGAAALDH1A1ALPG | |
| SCHEMBL14287628 | 0.81 | NPSR1 (0.72) | NPSR1MAPTGAAALDH1A1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467465-A | A kind of high-purity Latanoprost and its production and use | 上海天伟生物制药有限公司 | 2017-03-01 | — | — | CN | disclosed |
| WO-2016090461-A1 | SALTS OF PROSTAGLANDIN ANALOG INTERMEDIATES | APOTEX INC. (CA) | 2016-06-16 | — | — | WO | disclosed |
| US-5266710-A | (Exo,exo)-7-oxabicyclo[2.2.1]heptane-2,3-dimethanol; monoacyl ester and diacyl ester | PATEL RAMESH N (US) | 1993-11-30 | — | — | US | disclosed |
| US-5245055-A | Multistage, ylide intermediate, treatment of thrombosis | E. R. SQUIBB & SONS, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0491548-A2 | Processes and intermediates for thromboxane receptor antagonists | E.R. SQUIBB & SONS, INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| US-5084387-A | Enzyme hydrolytic deesterification and cyclization | E. R. SQUIBB & SONS, INC. (US) | 1992-01-28 | — | — | US | disclosed |
| US-5084581-A | Hydrolysis with alkali metal carbonate, bicarbonate or hydroxide and cyclization | E. R. SQUIBB & SONS, INC. (US) | 1992-01-28 | — | — | US | disclosed |
| US-4189606-A | ABOSTIFACIENT | GRUPPO LEPETIT S.P.A. (IT) | 1980-02-19 | — | — | US | disclosed |
| US-4182903-A | ABOSTIFACIENTS | GRUPPO LEPETIT S.P.A. (IT) | 1980-01-08 | — | — | US | disclosed |