Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | ALPG | P10696 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | NPY1R | P25929 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | NPY2R | P49146 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493538 | 1.00 | ALDH1A1 (1.00) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL10426396 | 1.00 | ALDH1A1 (1.00) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL4162470 | 0.97 | ALDH1A1 (0.95) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL1801537 | 0.92 | ALDH1A1 (0.86) | ALDH1A1NPSR1GAAMAPTALPG | |
| Hydrogen Peroxide SCHEMBL8610678 | 0.90 | ALDH1A1 (0.82) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL10985692 | 0.89 | NPSR1 (0.80) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL6767391 | 0.89 | NPSR1 (0.80) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL10404685 | 0.89 | NPSR1 (0.80) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL1726010 | 0.89 | NPSR1 (0.80) | ALDH1A1NPSR1GAAMAPTALPG | |
| SCHEMBL10870085 | 0.89 | NPSR1 (0.80) | ALDH1A1NPSR1GAAMAPTALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3114107-B1 | PROPELLANE DERIVATES AND SYNTHESIS | RECURIUM IP HOLDINGS LLC (US) | 2020-07-22 | — | — | EP | disclosed |
| US-10654812-B2 | Propellane derivates and synthesis | RECURIUM IP HOLDINGS LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20170081295-A1 | PROPELLANE DERIVATES AND SYNTHESIS | RECURIUM IP HOLDINGS, LLC | 2017-03-23 | — | — | US | disclosed |
| EP-3114107-A1 | PROPELLANE DERIVATES AND SYNTHESIS | Kalyra Pharmaceuticals Inc. (US) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134710-A1 | PROPELLANE DERIVATES AND SYNTHESIS | KALYRA PHARMACEUTICALS, INC. (US) | 2015-09-11 | — | — | WO | disclosed |
| US-8147921-B2 | Ink set for inkjet recording and inkjet recording method | FUJIFILM CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20080239045-A1 | INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081295-A1 | PROPELLANE DERIVATES AND SYNTHESIS | PDHA1, PDHA2, DHPS | ALDH1A1 23/4885NPSR1 3257/4885GAA 3435/4885 |
| US-10654812-B2 | Propellane derivates and synthesis | PDHA1, PDHA2, DHPS | ALDH1A1 23/4885NPSR1 3257/4885GAA 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.