SCHEMBL9463259

SCHEMBL9463259

CCCCCCCCCOP(=O)(Cl)Oc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.46
LPAR3 Q9UBY5 3/20 0.43
CETP P11597 3/20 0.43
LPAR1 Q92633 2/20 0.43
LPAR2 Q9HBW0 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9237969 0.92 LPAR3 (0.47) LPAR3LPAR1LPAR2
SCHEMBL30161634 0.92 L3MBTL1 (0.44)
SCHEMBL11466726 0.84 LTA4H (0.49) LTA4H
SCHEMBL2150716 0.84 LTA4H (0.49) LTA4H
SCHEMBL272117 0.84 LTA4H (0.49) LTA4H
SCHEMBL1726159 0.84 LTA4H (0.49) LTA4H
SCHEMBL8154565 0.84 LTA4H (0.49) LTA4H
SCHEMBL1548676 0.84 LTA4H (0.49) LTA4H
SCHEMBL125929 0.84 LTA4H (0.49) LTA4H
SCHEMBL3820549 0.84 LTA4H (0.49) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5208224-A Phosphorus containing compounds as antihypercholesterolemic and antiatherosclerotic agents WARNER-LAMBERT COMPANY (US) 1993-05-04 US disclosed