Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463674 | 0.87 | PTPN1 (0.40) | MAPTPTPN1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL9463750 | 0.86 | ADRB2 (0.51) | MAPTPTPN1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL9463824 | 0.85 | ADRB2 (0.52) | MAPTPTPN1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL9463830 | 0.85 | GAA (0.46) | MAPTPTPN1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL9463913 | 0.85 | PTPN1 (0.44) | MAPTPTPN1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL295552 | 0.84 | ALDH1A1 (0.57) | MAPTALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL9463664 | 0.83 | PTPN1 (0.40) | PTPN1ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL514607 | 0.82 | CA1 (0.44) | MAPTPTPN1ALDH1A1CA12CA1 | |
| SCHEMBL12482627 | 0.78 | ALDH1A1 (0.53) | MAPTALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL3943866 | 0.77 | ALDH1A1 (0.55) | MAPTALDH1A1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |