Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | VCP | P55072 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | PNP | P00491 | 7/20 | 0.58 |
| ▸ | HBB | P68871 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | EDNRA | P25101 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465137 | 0.87 | BLM (0.72) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9585855 | 0.86 | PDE3A (0.75) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9463803 | 0.85 | BLM (0.69) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9464100 | 0.85 | BLM (0.66) | BLMMEN1KMT2AALDH1A1LMNA | |
| Ganciclovir SCHEMBL27842151 | 0.84 | BLM (0.95) | BLMMEN1KMT2AALDH1A1LMNA | |
| Ganciclovir SCHEMBL2160505 | 0.84 | BLM (1.00) | BLMMEN1KMT2AALDH1A1LMNA | |
| Ganciclovir SCHEMBL3033 | 0.84 | BLM (1.00) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9463487 | 0.84 | BLM (0.64) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9464182 | 0.84 | BLM (0.64) | BLMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9463594 | 0.84 | BLM (0.64) | BLMMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |