⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610805 | 0.72 | — | — | |
| SCHEMBL20450729 | 0.70 | — | — | |
| SCHEMBL20465773 | 0.70 | — | — | |
| SCHEMBL10944574 | 0.69 | — | — | |
| SCHEMBL1585526 | 0.69 | — | — | |
| SCHEMBL19973271 | 0.67 | — | — | |
| SCHEMBL5466414 | 0.67 | — | — | |
| SCHEMBL20127094 | 0.67 | — | — | |
| SCHEMBL5456411 | 0.67 | — | — | |
| SCHEMBL9646071 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304805-A | Sealing leaks by polymerization of volatilized aminosilane monomers | Packo, Joseph J. (US) | 1981-12-08 | — | — | US | claimed |
| US-4237172-A | Sealing leaks by polymerization of volatilized aminosilane monomers | Packo, Joseph J. (US) | 1980-12-02 | — | — | US | claimed |
| US-20240074301-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-02-29 | — | — | US | disclosed |
| EP-2968336-A2 | COMBINATION OF AN EGFR T790M INHIBITOR AND AN EGFR INHIBITOR FOR THE TREATMENT OF NON-SMALL CELL LUNG CANCER | Pfizer Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014140989-A2 | COMBINATION OF AN EGFR T790M INHIBITOR AND AN EGFR INHIBITOR FOR THE TREATMENT OF NON-SMALL CELL LUNG CANCER | PFIZER INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| US-5254654-A | Molecular weight control | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1993-10-19 | — | — | US | disclosed |
| US-4304805-A | Sealing leaks by polymerization of volatilized aminosilane monomers | Packo, Joseph J. (US) | 1981-12-08 | — | — | US | disclosed |