Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463643 | 0.90 | LPAR1 (0.71) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL16846413 | 0.89 | TDP1 (0.60) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL29053751 | 0.86 | TDP1 (0.66) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL3185725 | 0.84 | TDP1 (0.68) | TDP1ADRB2ADRB1ADRB3KEAP1 | |
| SCHEMBL28182817 | 0.83 | TDP1 (1.00) | TDP1KEAP1APPALDH1A1MAPT | |
| SCHEMBL1983179 | 0.82 | ADRB2 (0.66) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL24088559 | 0.82 | LMNA (0.59) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL9463746 | 0.81 | ADRB2 (0.68) | LPAR1ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL30547113 | 0.81 | TDP1 (0.64) | TDP1ADRB2ADRB1ADRB3KEAP1 | |
| SCHEMBL12873308 | 0.81 | TDP1 (0.64) | TDP1LPAR1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |