Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825388 | 0.91 | KEAP1 (0.57) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL23141160 | 0.89 | KEAP1 (0.61) | KMT2AKEAP1ALDH1A1MAPTALOX12 | |
| SCHEMBL59151 | 0.86 | KEAP1 (0.64) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL9387480 | 0.83 | KEAP1 (0.76) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL9464239 | 0.80 | KEAP1 (0.49) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL9464347 | 0.80 | KEAP1 (0.49) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL3081180 | 0.79 | KEAP1 (1.00) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| Sulfabenz SCHEMBL193566 | 0.79 | KMT2A (1.00) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL9464922 | 0.78 | KEAP1 (0.50) | KMT2AKEAP1ALDH1A1MAPTHTT | |
| SCHEMBL9464234 | 0.77 | POLB (0.46) | KMT2AKEAP1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204453-A | Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0241414-B1 | PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES | CIBA-GEIGY AG (CH) | 1991-05-08 | — | — | EP | disclosed |
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0121495-A1 | Monoazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |