Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464234 | 0.81 | POLB (0.46) | KEAP1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL9464347 | 0.80 | KEAP1 (0.49) | KEAP1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL9464302 | 0.80 | KMT2A (0.66) | KEAP1KMT2AALDH1A1MAPTCA1 | |
| SCHEMBL28825388 | 0.80 | KEAP1 (0.57) | KEAP1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL2240809 | 0.78 | ALDH1A1 (0.71) | KEAP1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL3653048 | 0.75 | KEAP1 (0.59) | KEAP1KMT2AALDH1A1MAPTTP53 | |
| SCHEMBL28227612 | 0.74 | ALDH1A1 (0.51) | KEAP1ALDH1A1TSHRTHRBMAPT | |
| SCHEMBL7027050 | 0.74 | MAPT (0.64) | KMT2AALDH1A1THRBMAPTKDM4E | |
| SCHEMBL9464922 | 0.72 | KEAP1 (0.50) | KEAP1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2573702 | 0.72 | ALDH1A1 (0.53) | KEAP1ALDH1A1TSHRTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204453-A | Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0241414-B1 | PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES | CIBA-GEIGY AG (CH) | 1991-05-08 | — | — | EP | disclosed |
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0121495-A1 | Monoazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |