Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465242 | 0.94 | AVPR1B (0.40) | ADRA1AHRH1ADRA1BAVPR1BPIK3CB | |
| SCHEMBL9465729 | 0.92 | ADRA1A (0.45) | ADRA1AHRH1ADRA1BAVPR1BALDH1A1 | |
| SCHEMBL9465019 | 0.90 | MAPT (0.43) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9465742 | 0.90 | SLC2A1 (0.41) | ADRA1AHRH1ADRA1BNPC1RAB9A | |
| SCHEMBL9465004 | 0.90 | MAPT (0.41) | ADRA1AHRH1ADRA1BAVPR1BALDH1A1 | |
| SCHEMBL9465076 | 0.89 | MAPT (0.37) | ALDH1A1MAPTCCR2 | |
| SCHEMBL9464543 | 0.89 | PIK3CA (0.39) | PIK3CAMAPTPIK3CD | |
| SCHEMBL9465088 | 0.86 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL9464951 | 0.86 | ADRA1A (0.41) | ADRA1AHRH1ADRA1BAVPR1BALDH1A1 | |
| SCHEMBL9465782 | 0.85 | ADRA1A (0.40) | ADRA1AHRH1ADRA1BAVPR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |