Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | USP2 | O75604 | 8/20 | 0.40 |
| ▸ | CASP1 | P29466 | 8/20 | 0.40 |
| ▸ | CASP7 | P55210 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464688 | 0.81 | LMNA (0.37) | CYP1A2MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL9464600 | 0.81 | LMNA (0.38) | CYP1A2MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL9465308 | 0.79 | LMNA (0.40) | CYP1A2MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL9464664 | 0.79 | ALDH1A1 (0.45) | CYP1A2MEN1USP2CASP1CASP7 | |
| SCHEMBL9465059 | 0.77 | TDP1 (0.39) | CYP1A2MEN1USP2CASP1CASP7 | |
| SCHEMBL9465036 | 0.76 | ALDH1A1 (0.41) | CYP1A2MEN1USP2CASP1CASP7 | |
| SCHEMBL9464824 | 0.75 | LMNA (0.39) | CYP1A2KMT2ACYP3A4ALDH1A1HIF1A | |
| SCHEMBL9464965 | 0.74 | CNR2 (0.41) | CYP1A2KMT2ACYP3A4ALDH1A1CLK4 | |
| SCHEMBL9464936 | 0.72 | HRH4 (0.42) | CYP1A2CYP3A4HSD17B10CYP2C19L3MBTL1 | |
| SCHEMBL9464781 | 0.71 | DPP4 (0.39) | ALDH1A1TSHRPOLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |