Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464746 | 0.78 | NR1H2 (0.47) | NR1H2NR1H3ATMPOLBNPC1 | |
| SCHEMBL9465143 | 0.77 | NR1H2 (0.53) | NR1H2NR1H3ATMNPSR1POLB | |
| SCHEMBL26730596 | 0.70 | KDM4E (0.42) | ATMNPSR1POLBNPC1RAB9A | |
| SCHEMBL9465535 | 0.69 | NR1H2 (0.61) | NR1H2NR1H3ATMNPSR1POLB | |
| SCHEMBL1436121 | 0.69 | NR1H2 (0.61) | NR1H2NR1H3POLBNPC1RAB9A | |
| SCHEMBL1786764 | 0.68 | POLB (0.68) | ATMNPSR1POLBNPC1RAB9A | |
| SCHEMBL29480990 | 0.68 | POLB (0.68) | ATMNPSR1POLBNPC1RAB9A | |
| SCHEMBL28987575 | 0.68 | HPGD (0.47) | POLBSMN1; SMN2TP53CYP1A2HPGD | |
| SCHEMBL12089075 | 0.68 | NR1H2 (0.60) | NR1H2NR1H3POLBNPC1RAB9A | |
| SCHEMBL11180907 | 0.68 | NR1H2 (0.60) | NR1H2NR1H3NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |