Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465116 | 0.82 | NR1H2 (0.50) | NR1H2NR1H3RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9464804 | 0.77 | NR1H2 (0.49) | NR1H2NR1H3LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1436121 | 0.76 | NR1H2 (0.61) | NR1H2NR1H3LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9465535 | 0.73 | NR1H2 (0.61) | NR1H2NR1H3LMNARAB9APOLB | |
| SCHEMBL17637927 | 0.72 | AKT2 (0.63) | LMNARAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL10131903 | 0.70 | AKT2 (0.61) | LMNARAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL666693 | 0.70 | NR1H2 (1.00) | NR1H2NR1H3LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11480060 | 0.69 | NPSR1 (0.63) | LMNARAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL11575048 | 0.69 | NR1H2 (0.52) | NR1H2NR1H3LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28146139 | 0.69 | NR1H2 (1.00) | NR1H2NR1H3LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |