Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.61 |
| ▸ | PARP1 | P09874 | 4/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465025 | 0.86 | NR1H2 (0.48) | NR1H2NR1H3PARP1ARPOLB | |
| SCHEMBL9464798 | 0.86 | ALDH1A1 (0.49) | NR1H2NR1H3PARP1ARNPC1 | |
| SCHEMBL1528283 | 0.76 | NR1H2 (1.00) | NR1H2NR1H3NPC1RAB9APOLB | |
| SCHEMBL10743236 | 0.73 | PARP1 (0.63) | PARP1ARALDH1A1HPGDCYP2C9 | |
| SCHEMBL9465143 | 0.73 | NR1H2 (0.53) | NR1H2NR1H3NPC1RAB9APOLB | |
| SCHEMBL863462 | 0.71 | AR (1.00) | PARP1ARCYP2C9LMNAPRMT5 | |
| SCHEMBL7874800 | 0.69 | HPGD (0.75) | PARP1ARALDH1A1HPGDCYP2C9 | |
| SCHEMBL9464804 | 0.69 | NR1H2 (0.49) | NR1H2NR1H3NPC1RAB9APOLB | |
| SCHEMBL11706631 | 0.69 | PARP1 (0.53) | NR1H2NR1H3PARP1ARALDH1A1 | |
| SCHEMBL1752918 | 0.68 | MAPT (0.68) | PARP1ARRAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |