Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK3 | O43293 | 7/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464880 | 1.00 | DAPK3 (0.69) | DAPK3GAANOTUMPLCG2ALOX5 | |
| SCHEMBL9464738 | 0.93 | DAPK3 (0.75) | DAPK3GAANOTUMPLCG2ALOX5 | |
| SCHEMBL9464734 | 0.93 | DAPK3 (0.75) | DAPK3GAANOTUMPLCG2ALOX5 | |
| SCHEMBL6791976 | 0.88 | DAPK3 (0.61) | DAPK3GAANOTUMALOX5CSNK2A2 | |
| SCHEMBL6791970 | 0.88 | DAPK3 (0.61) | DAPK3GAANOTUMALOX5CSNK2A2 | |
| SCHEMBL2131615 | 0.86 | DAPK3 (0.75) | DAPK3GAANOTUMPLCG2ALOX5 | |
| SCHEMBL2131623 | 0.86 | DAPK3 (0.75) | DAPK3GAANOTUMPLCG2ALOX5 | |
| SCHEMBL4691058 | 0.86 | DAPK3 (0.75) | DAPK3GAANOTUMPLCG2ALOX5 | |
| SCHEMBL24418239 | 0.85 | ALOX5 (0.71) | DAPK3GAANOTUMPLCG2ALOX5 | |
| SCHEMBL6795692 | 0.85 | DAPK3 (0.73) | DAPK3GAANOTUMPLCG2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |