SCHEMBL9465121

SCHEMBL9465121

Cc1ncc(C2=N[N]C=C2)s1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.33
AOC3 Q16853 2/20 0.32
ADORA2A P29274 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10442596 0.73 HCAR2 (0.46) HCAR2AOC3ADORA2ACYP11B1CYP11B2
SCHEMBL9465935 0.72 NPC1 (0.37)
SCHEMBL9465604 0.70 NPC1 (0.48) CYP11B1CYP11B2
SCHEMBL9465991 0.69 NOS1 (0.38) ADORA2A
SCHEMBL9465837 0.67 GSK3B (0.31)
SCHEMBL20175445 0.66 HCAR2 (0.40) HCAR2AOC3ADORA2ACYP11B1CYP11B2
SCHEMBL9465496 0.65 HDAC8 (0.39)
SCHEMBL14435919 0.65 AOC3 (0.47) HCAR2AOC3ADORA2A
SCHEMBL5209803 0.65 COMT (0.41)
SCHEMBL2405110 0.64 HPGDS (0.43) HCAR2AOC3ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed