SCHEMBL9465130

SCHEMBL9465130

O=CNc1cc(=O)n(-c2ccccc2)[nH]1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.51
LMNA P02545 2/20 0.51
POLB P06746 1/20 0.51
BLM P54132 1/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TSHR P16473 2/20 0.47
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
ALKBH5 Q6P6C2 4/20 0.41
MPI P34949 1/20 0.41
RAB9A P51151 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
CTSA P10619 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7039254 0.81 MAPT (0.50) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL11234970 0.79 MAPT (0.49) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL10915383 0.77 TSHR (0.52) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL7626297 0.76 TSHR (0.48) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL9763528 0.76 ALKBH5 (0.50) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL11785437 0.76 ALDH1A1 (0.45) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL11863478 0.74 TSHR (0.53) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL11439427 0.74 ALDH1A1 (0.51) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL11326057 0.74 TSHR (0.50) ALDH1A1MAPTLMNAPOLBBLM
SCHEMBL11445425 0.74 TSHR (0.50) ALDH1A1MAPTLMNAPOLBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0278910-B1 HEAVY METAL COMPLEX DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
EP-0241414-B1 PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES CIBA-GEIGY AG (CH) 1991-05-08 EP disclosed
US-5001227-A Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand CIBA-GEIGY CORPORATION (US) 1991-03-19 US disclosed
US-4990598-A Colorfastness CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK 1991-02-05 US disclosed
US-4960870-A DYEING WOOL, POLYAMIDES; FIBER REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1990-10-02 US disclosed
EP-0142104-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-01-03 EP disclosed
US-4874391-A USING WATER SOLUBLE COPPER COMPLEX AZO DYE, LIGHT STABILIZER AND ANTIOXIDANT CIBA-GEIGY CORPORATION (US) 1989-10-17 US disclosed
EP-0141416-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-08-16 EP disclosed
US-4813972-A USING LEVELING DYES, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1989-03-21 US disclosed
EP-0185611-A1 Process for the photochemical stabilisation of synthetic fibrous materials containing polyamide fibres CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
EP-0159962-A2 Fibre-reactive chromium or cobalt complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-30 EP disclosed
EP-0144776-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0061998-B1 USE OF 1:2-CHROME OR COBALT COMPLEX DYES FOR DYEING LEATHER OR FURS CIBA-GEIGY AG (CH) 1985-04-03 EP disclosed
US-4425133-A AZO DYES CIBA-GEIGY CORPORATION (US) 1984-01-10 US disclosed
EP-0061998-A1 Use of 1:2-chrome or cobalt complex dyes for dyeing leather or furs CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed
US-4101543-A DYES FOR CELLULOSE ACETATES, AROMATIC POLYESTERS OR POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US disclosed
US-4052376-A POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-10-04 US disclosed
US-4010151-A Water insoluble mono azo and disazo dyes containing cinnamonitrile group PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-01 US disclosed
US-4008213-A WATER INSOLUBLE UGINE KUHLMANN (FR) 1977-02-15 US disclosed