Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9466527 | 0.99 | CD274 (0.36) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| SCHEMBL29449853 | 0.93 | CD274 (0.40) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| SCHEMBL10488246 | 0.93 | CD274 (0.40) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| SCHEMBL10488277 | 0.92 | SLC2A1 (0.39) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| Hydrochloric Acid SCHEMBL10488206 | 0.92 | CD274 (0.39) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| Hydrochloric Acid SCHEMBL10488368 | 0.90 | SLC2A1 (0.39) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| SCHEMBL10488292 | 0.88 | CD274 (0.39) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| SCHEMBL10488302 | 0.86 | CD274 (0.38) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| Hydrochloric Acid SCHEMBL10488528 | 0.84 | CD274 (0.38) | CD274CYP1A2KMT2ANPBWR1MCHR1 | |
| SCHEMBL10488248 | 0.82 | KDM4E (0.47) | CD274CYP1A2KMT2ANPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5241107-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | claimed |
| US-5241107-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | disclosed |