Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482999 | 0.75 | TSHR (0.36) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL19285040 | 0.73 | TSHR (0.35) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL2291884 | 0.73 | TSHR (0.35) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL19285495 | 0.73 | TSHR (0.35) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL28418416 | 0.71 | TSHR (0.33) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL9655752 | 0.70 | TSHR (0.34) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL11360367 | 0.67 | TSHR (0.38) | TSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL9656014 | 0.67 | SLC6A3 (0.38) | TSHRALDH1A1SLC6A2SLC6A4BLM | |
| SCHEMBL28300968 | 0.66 | TSHR (0.42) | TSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL98442 | 0.65 | TSHR (0.33) | TSHRALDH1A1SLC6A2SLC6A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194549-A | Polypropylene substrate with polymer coating with olefin, acrylic and copolyene monomers | ICI RESINS BV (NL) | 1993-03-16 | — | — | US | claimed |
| EP-0468644-A1 | Coating composition and polymer for use therein | ZENECA RESINS BV (NL) | 1992-01-29 | — | — | EP | claimed |
| US-5194549-A | Polypropylene substrate with polymer coating with olefin, acrylic and copolyene monomers | ICI RESINS BV (NL) | 1993-03-16 | — | — | US | disclosed |
| EP-0468644-A1 | Coating composition and polymer for use therein | ZENECA RESINS BV (NL) | 1992-01-29 | — | — | EP | disclosed |