Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656014 | 0.83 | SLC6A3 (0.38) | TSHRCYP2C19CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15416750 | 0.79 | CA2 (0.44) | TSHRCYP2C19CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9653986 | 0.78 | TSHR (0.32) | TSHRCYP2C19CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11659905 | 0.78 | GPR84 (0.41) | BLMCA2MAPK1 | |
| SCHEMBL8743596 | 0.76 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL6482999 | 0.73 | TSHR (0.36) | TSHRCYP2C19CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL19285040 | 0.71 | TSHR (0.35) | TSHRCYP2C19CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL2291884 | 0.71 | TSHR (0.35) | TSHRCYP2C19CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL19285495 | 0.71 | TSHR (0.35) | TSHRCYP2C19CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8689396 | 0.70 | TSHR (0.38) | TSHRCYP2C19CYP2D6SLC6A3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222157-B1 | RESIN COMPOSITION | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-12-30 | — | — | EP | claimed |