Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687832 | 0.87 | PDE4A (0.36) | PTGS2PPARGKDM4E | |
| SCHEMBL10044413 | 0.82 | PTGS2 (0.53) | PTGS2LMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7926564 | 0.81 | GAA (0.44) | PTGS2LMNAPPARGMMP2MMP3 | |
| SCHEMBL14074048 | 0.81 | PTGS2 (0.38) | PTGS2LMNAALDH1A1PPARGCYP1A2 | |
| SCHEMBL10044416 | 0.79 | PTGS2 (0.43) | PTGS2LMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10196841 | 0.78 | GAA (0.40) | PTGS2LMNAALDH1A1MMP2MMP3 | |
| SCHEMBL11356386 | 0.76 | PTGS2 (0.42) | PTGS2LMNAALDH1A1MMP2MMP3 | |
| SCHEMBL18102200 | 0.76 | LMNA (0.36) | PTGS2LMNAALDH1A1PPARGMMP2 | |
| SCHEMBL14074024 | 0.73 | SMN1; SMN2 (0.41) | PTGS2LMNAALDH1A1MMP2MMP3 | |
| SCHEMBL14446918 | 0.73 | LMNA (0.59) | LMNAALDH1A1TP53KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34201-E | Analgesics | ANAQUEST, INC. (US) | 1993-03-23 | — | — | US | disclosed |
| US-5053411-A | Analgesics | ANAQUEST, INC. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0396282-A2 | N-aryl-N-[4-(heterocyclicalkyl) piperidinyl]amides and pharmaceutical compositions and methods employing such compounds | BOC, INC. (US) | 1990-11-07 | — | — | EP | disclosed |