Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175441 | 0.95 | HTR1A (0.57) | HTR1ADRD2 | |
| SCHEMBL9181481 | 0.82 | HTR1A (0.48) | HTR1ADRD2 | |
| SCHEMBL10516639 | 0.80 | HTR1A (0.68) | HTR1ADRD2 | |
| SCHEMBL8520072 | 0.77 | HTR1A (0.48) | HTR1ADRD2 | |
| SCHEMBL13533025 | 0.77 | HTR1A (0.83) | HTR1ADRD2 | |
| SCHEMBL10513645 | 0.76 | — | — | |
| SCHEMBL10514665 | 0.74 | — | — | |
| SCHEMBL10524008 | 0.73 | — | — | |
| SCHEMBL10515450 | 0.73 | — | — | |
| SCHEMBL13533028 | 0.72 | HTR1A (1.00) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |