Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909471 | 0.75 | MIF (0.60) | MIFALDH1A1 | |
| SCHEMBL7435006 | 0.67 | CA2 (0.40) | ALDH1A1CA2CA4CA5A | |
| SCHEMBL10863572 | 0.67 | MIF (0.50) | MIFALDH1A1 | |
| SCHEMBL17067443 | 0.67 | MIF (0.50) | MIFALDH1A1 | |
| SCHEMBL21398528 | 0.67 | MIF (0.50) | MIFALDH1A1 | |
| SCHEMBL5925 | 0.66 | — | — | |
| Benzene SCHEMBL11510532 | 0.66 | MIF (0.55) | MIFALDH1A1 | |
| SCHEMBL1332539 | 0.66 | — | — | |
| SCHEMBL245090 | 0.66 | MIF (0.55) | MIFALDH1A1 | |
| SCHEMBL19459346 | 0.66 | MIF (0.55) | MIFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105267-B1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-12-10 | — | — | EP | claimed |
| EP-0105267-A1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN. | SCHERING AG (DE) | 1984-04-18 | — | — | EP | claimed |
| WO-1983001449-A1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN | VORBRÜGGEN, Helmut | 1983-04-28 | — | — | WO | claimed |
| US-5235072-A | 2-OXABICYCLO(2,2,1)HEPTANE DERIVATIVES AND PHARMACEUTICAL | SCHERING AKTIENGSELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |
| EP-0358290-B1 | 2-Oxa-bicyclo[2.2.1]heptane derivatives and medicines containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |
| WO-1990002740-A1 | 2-OXA-BICYCLO[2.2.1]HEPTANE DERIVATIVES AND DRUGS CONTAINING SAID COMPOUNDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-03-22 | — | — | WO | disclosed |
| EP-0358290-A1 | 2-Oxa-bicyclo[2.2.1]heptane derivatives and medicines containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0105267-B1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-12-10 | — | — | EP | disclosed |
| EP-0105267-B1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-12-10 | — | — | EP | disclosed |
| US-4554363-A | Process for the preparation of carbacyclin intermediates | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-11-19 | — | — | US | disclosed |
| US-4554363-A | Process for the preparation of carbacyclin intermediates | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-11-19 | — | — | US | disclosed |
| EP-0105267-A1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN. | SCHERING AG (DE) | 1984-04-18 | — | — | EP | disclosed |
| EP-0105267-A1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN. | SCHERING AG (DE) | 1984-04-18 | — | — | EP | disclosed |
| WO-1983001449-A1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN | VORBRÜGGEN, Helmut | 1983-04-28 | — | — | WO | disclosed |
| WO-1983001449-A1 | METHOD FOR THE PREPARATION OF INTERMEDIARY COMPOUNDS OF CARBACYCLIN | VORBRÜGGEN, Helmut | 1983-04-28 | — | — | WO | disclosed |