SCHEMBL9467152

SCHEMBL9467152

OCC(=CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CO

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9466986 1.00 THRB (0.31) THRBLMNA
SCHEMBL9468177 1.00 THRB (0.31) THRBLMNA
SCHEMBL9467715 0.98
SCHEMBL3767050 0.74 THRB (0.30) THRB
SCHEMBL3767053 0.74 THRB (0.30) THRB
SCHEMBL951360 0.72 LMNA (0.35) THRBLMNA
SCHEMBL1451051 0.72 LMNA (0.35) THRBLMNA
SCHEMBL1033831 0.72 LMNA (0.35) THRBLMNA
SCHEMBL18499726 0.70 LMNA (0.33) THRBLMNA
SCHEMBL10456717 0.70 LMNA (0.33) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5254660-A Polyurethanes, fluoropolymers BAYER AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
EP-0540976-A1 Use of polyisocyanate solutions for the impregnation of mineral substrates BAYER AG (DE) 1993-05-12 EP disclosed