Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129817 | 0.81 | CYP19A1 (0.50) | CYP2C19LMNAKDM4ECYP19A1 | |
| SCHEMBL2168324 | 0.81 | CYP19A1 (0.61) | CYP2C19LMNAKDM4ECYP19A1 | |
| SCHEMBL9786766 | 0.80 | CYP3A4 (0.45) | TSHRMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL10938573 | 0.80 | CYP19A1 (0.44) | CYP2C19LMNAKDM4EBACE1CYP19A1 | |
| SCHEMBL5858162 | 0.79 | TSHR (0.42) | TSHRMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL9303403 | 0.75 | SLC6A2 (0.43) | TSHRMEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL15955086 | 0.74 | MAOA (0.60) | TSHRMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL11840135 | 0.74 | CYP19A1 (0.71) | TSHRMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL11841553 | 0.74 | CYP19A1 (0.71) | TSHRMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL9786753 | 0.74 | KDM4E (0.39) | TSHRMEN1CYP1A2POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34201-E | Analgesics | ANAQUEST, INC. (US) | 1993-03-23 | — | — | US | disclosed |
| US-5071857-A | Anticarcinogenic agent | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-12-10 | — | — | US | disclosed |
| US-5053411-A | Analgesics | ANAQUEST, INC. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0396282-A2 | N-aryl-N-[4-(heterocyclicalkyl) piperidinyl]amides and pharmaceutical compositions and methods employing such compounds | BOC, INC. (US) | 1990-11-07 | — | — | EP | disclosed |
| EP-0169062-B1 | GLUTARIMIDE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-04-19 | — | — | EP | disclosed |
| EP-0147121-B1 | 2,6-DIOXOPIPERIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-02-03 | — | — | EP | disclosed |
| US-4668689-A | 3-ALKYL-3-PYRIDYL) DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-05-26 | — | — | US | disclosed |
| EP-0169062-A1 | Glutarimide derivatives, their preparation and pharmaceutical compositions containing them | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-01-22 | — | — | EP | disclosed |
| EP-0147121-A1 | 2,6-Dioxopiperidine derivatives, their preparation and pharmaceutical compositions containing them | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-07-03 | — | — | EP | disclosed |
| WO-1985002618-A1 | 2,6-DIOXOPIPERIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-06-20 | — | — | WO | disclosed |