Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL9303273 | 0.93 | SLC6A2 (0.40) | SLC6A2SLC6A4L3MBTL1MEN1KMT2A | |
| SCHEMBL9303006 | 0.77 | LMNA (0.37) | SLC6A4MEN1KMT2AICMTBACE1 | |
| SCHEMBL9467170 | 0.75 | TSHR (0.47) | SLC6A2SLC6A4MEN1KMT2ABACE1 | |
| SCHEMBL9304202 | 0.73 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9869620 | 0.72 | SIGMAR1 (0.49) | SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL9633447 | 0.70 | BACE1 (0.38) | SLC6A2SLC6A4MEN1KMT2ABACE1 | |
| SCHEMBL9303707 | 0.69 | SCN1A (0.38) | SLC6A4CYP3A4SIGMAR1 | |
| SCHEMBL9303335 | 0.68 | SIGMAR1 (0.45) | KMT2ASIGMAR1 | |
| SCHEMBL9302750 | 0.66 | DDB1 (0.37) | SLC6A2SLC6A4BACE1TSHRHTR2C | |
| SCHEMBL5213777 | 0.64 | SLC6A2 (0.54) | SLC6A2SLC6A4MEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1991009014-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |