Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216978 | 0.85 | LTA4H (0.43) | CA4LTA4HTDP1L3MBTL1ATM | |
| SCHEMBL210129 | 0.83 | CA4 (0.41) | CA4LTA4HTDP1L3MBTL1TSHR | |
| SCHEMBL27595853 | 0.80 | CA4 (0.39) | CA4LTA4HTDP1L3MBTL1TSHR | |
| SCHEMBL27349424 | 0.80 | CA4 (0.39) | CA4LTA4HTDP1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL21273293 | 0.80 | CA4 (0.39) | CA4LTA4HTDP1L3MBTL1TSHR | |
| SCHEMBL28493117 | 0.78 | CA4 (0.38) | CA4LTA4HTDP1L3MBTL1TSHR | |
| Nitrogen SCHEMBL27853278 | 0.78 | CA4 (0.38) | CA4LTA4HTDP1L3MBTL1TSHR | |
| Toluene SCHEMBL27867022 | 0.74 | ACHE (0.52) | CA4TDP1TSHRHPGDKMT2A | |
| Phosphoric Acid SCHEMBL28400020 | 0.74 | SRC (0.48) | CA4TDP1L3MBTL1ATMTSHR | |
| SCHEMBL7867520 | 0.71 | CA4 (0.42) | CA4LTA4HTDP1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235072-A | 2-OXABICYCLO(2,2,1)HEPTANE DERIVATIVES AND PHARMACEUTICAL | SCHERING AKTIENGSELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |
| EP-0358290-B1 | 2-Oxa-bicyclo[2.2.1]heptane derivatives and medicines containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |
| EP-0358290-A1 | 2-Oxa-bicyclo[2.2.1]heptane derivatives and medicines containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-03-14 | — | — | EP | disclosed |