Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467283 | 0.93 | HTR1A (0.41) | HTR1APOLB | |
| SCHEMBL9183283 | 0.85 | HTR1A (0.56) | HTR1A | |
| SCHEMBL9685587 | 0.84 | — | — | |
| SCHEMBL9177843 | 0.82 | — | — | |
| SCHEMBL9173735 | 0.81 | HTR1A (0.43) | HTR1A | |
| SCHEMBL9467135 | 0.77 | HTR1A (0.51) | HTR1A | |
| SCHEMBL9467347 | 0.76 | — | — | |
| SCHEMBL9685582 | 0.76 | — | — | |
| SCHEMBL9183269 | 0.76 | POLB (0.39) | POLB | |
| SCHEMBL9177834 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |
| EP-0490772-A1 | 1,4-Disubstituted piperazines, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-06-17 | — | — | EP | disclosed |