Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467351 | 1.00 | DRD4 (0.50) | DRD4SIGMAR1DRD2 | |
| SCHEMBL1038532 | 0.94 | HTR2C (0.44) | — | |
| SCHEMBL9175625 | 0.94 | HTR2C (0.44) | — | |
| SCHEMBL9176453 | 0.92 | DRD2 (0.45) | DRD4SIGMAR1DRD2 | |
| SCHEMBL9467335 | 0.92 | DRD2 (0.45) | DRD4SIGMAR1DRD2 | |
| SCHEMBL9177231 | 0.89 | DRD4 (0.46) | DRD4 | |
| SCHEMBL9180749 | 0.89 | DRD4 (0.46) | DRD4 | |
| SCHEMBL9466299 | 0.88 | SIGMAR1 (0.47) | DRD4SIGMAR1DRD2 | |
| SCHEMBL9175522 | 0.88 | SIGMAR1 (0.47) | DRD4SIGMAR1DRD2 | |
| SCHEMBL9465608 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |