Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796986 | 1.00 | LMNA (0.52) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL998338 | 0.97 | LMNA (0.48) | LMNAALDH1A1THRB | |
| SCHEMBL21476 | 0.87 | LMNA (0.42) | LMNAALDH1A1THRB | |
| SCHEMBL70845 | 0.87 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL343041 | 0.87 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2354992 | 0.87 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL16516576 | 0.87 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL10777196 | 0.87 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL570305 | 0.87 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1132272 | 0.87 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448416-A1 | ANTIMICROBIAL/PRESERVATIVE COMPOSITIONS COMPRISING BOTANICALS | The Trustees of Columbia University in the City of New York (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002929-A1 | ANTIMICROBIAL/PRESERVATIVE COMPOSITIONS COMPRISING BOTANICALS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-01-06 | — | — | WO | disclosed |