Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645827 | 1.00 | LMNA (0.39) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL2300682 | 0.97 | LMNA (0.41) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL18989253 | 0.90 | LMNA (0.35) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL21477 | 0.90 | LMNA (0.42) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL4850732 | 0.85 | TRPV1 (0.37) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL7455782 | 0.85 | TRPV1 (0.40) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL3708212 | 0.84 | PTPN1 (0.35) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL11154922 | 0.84 | LMNA (0.61) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL1043717 | 0.82 | LMNA (0.41) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL27868495 | 0.82 | THRB (0.39) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448416-A1 | ANTIMICROBIAL/PRESERVATIVE COMPOSITIONS COMPRISING BOTANICALS | The Trustees of Columbia University in the City of New York (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002929-A1 | ANTIMICROBIAL/PRESERVATIVE COMPOSITIONS COMPRISING BOTANICALS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-01-06 | — | — | WO | disclosed |
| EP-0957903-A4 | PHARMACEUTICAL COMPOSITIONS AND METHODS | CODON PHARMACEUTICALS INC (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-0957903-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | Codon Pharmaceuticals, Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998011882-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | CODON PHARMACEUTICALS, INC. (US) | 1998-03-26 | — | — | WO | disclosed |