SCHEMBL9467648

SCHEMBL9467648

O=C(O)CC1C=CC=CC1CC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A12 P48065 6/20 0.35
SLC6A11 P48066 6/20 0.35
SLC6A13 Q9NSD5 6/20 0.35
SLC6A1 P30531 3/20 0.32
GABRA5 P31644 3/20 0.32
GABRB2 P47870 3/20 0.32
GABRA1 P14867 2/20 0.32
GABRR1 P24046 2/20 0.32
GABRA4 P48169 2/20 0.32
HSD11B1 P28845 1/20 0.32
ITGB3 P05106 1/20 0.31
ITGB2 P05107 1/20 0.31
ITGB1 P05556 1/20 0.31
ITGAV P06756 1/20 0.31
ITGA2B P08514 1/20 0.31
ITGA5 P08648 1/20 0.31
ITGB5 P18084 1/20 0.31
ITGAL P20701 1/20 0.31
APEX1 P27695 1/20 0.30
GRM2 Q14416 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11550576 0.77
SCHEMBL16842720 0.76 FFAR3 (0.36) SLC6A12SLC6A11SLC6A13
SCHEMBL16599682 0.69 SLC6A12 (0.31) SLC6A12SLC6A11SLC6A13
SCHEMBL28449801 0.69
SCHEMBL6256551 0.66 SLC6A12 (0.32) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL28737614 0.63 HSD11B1 (0.52) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL1237980 0.63 SLC6A12 (0.44) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL21642939 0.63 SLC6A12 (0.39) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL2788386 0.63 SLC6A12 (0.44) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL2788384 0.63 SLC6A12 (0.44) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5248734-A Aromatization of a substituted polycyclohexadiene polymer CORNELL RESEARCH FOUNDATION, INC. (US) 1993-09-28 US claimed
US-5248734-A Aromatization of a substituted polycyclohexadiene polymer CORNELL RESEARCH FOUNDATION, INC. (US) 1993-09-28 US disclosed