Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26137542 | 0.87 | CYP3A4 (0.39) | CYP2D6ALDH1A1CYP3A4NFE2L2MAPT | |
| SCHEMBL26137543 | 0.86 | CYP3A4 (0.38) | CYP2D6ALDH1A1CYP3A4NFE2L2MAPT | |
| SCHEMBL13790221 | 0.82 | CYP2D6 (0.50) | CYP2D6GRIK1GRIK2PIM1PIM2 | |
| SCHEMBL9060858 | 0.81 | NFE2L2 (0.62) | CYP2D6ALDH1A1CYP3A4NFE2L2MAPT | |
| SCHEMBL9060861 | 0.81 | NFE2L2 (0.62) | CYP2D6ALDH1A1CYP3A4NFE2L2MAPT | |
| SCHEMBL9967779 | 0.80 | MAPT (0.46) | CYP2D6PIM1PIM2ALDH1A1CYP3A4 | |
| SCHEMBL3844916 | 0.79 | KDM4E (0.57) | PDE2ACYP2D6GRIK1GRIK2PIM1 | |
| SCHEMBL24434700 | 0.78 | CYP3A4 (0.61) | CYP2D6ALDH1A1CYP3A4NFE2L2MAPT | |
| SCHEMBL9967708 | 0.78 | CYP3A4 (0.61) | CYP2D6ALDH1A1CYP3A4NFE2L2MAPT | |
| SCHEMBL9061561 | 0.77 | RELA (0.59) | CYP2D6PIM1PIM2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160280-B2 | Pesticial compounds | BASF SE (DE) | 2021-11-02 | — | — | US | disclosed |
| US-20200029566-A1 | Pesticial Compounds | BASF SE (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER IP GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER IP GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-9006265-B2 | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-9006265-B2 | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | DHPS, FDPS, DPYD | PDE2A 2251/4885CYP2D6 764/4885GRIK1 781/4885 |
| US-11160280-B2 | Pesticial compounds | PNMT, DDT, NIT2 | PDE2A 386/4885CYP2D6 1333/4885GRIK1 3232/4885 |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | DHPS, FDPS, DPYD | PDE2A 2251/4885CYP2D6 764/4885GRIK1 781/4885 |
| US-20200029566-A1 | Pesticial Compounds | PNMT, DDT, NIT2 | PDE2A 386/4885CYP2D6 1333/4885GRIK1 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.