Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1209573 | 0.85 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2LMNAKCNA5TBXAS1 | |
| SCHEMBL2370434 | 0.83 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2LMNAKCNA5TBXAS1 | |
| SCHEMBL12883291 | 0.83 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2LMNAKCNA5TBXAS1 | |
| SCHEMBL9519691 | 0.82 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2LMNAKCNA5TBXAS1 | |
| SCHEMBL23685640 | 0.81 | L3MBTL1 (0.59) | L3MBTL1SMN1; SMN2LMNAKCNA5MEN1 | |
| SCHEMBL6199618 | 0.81 | PLOD2 (0.53) | L3MBTL1SMN1; SMN2LMNAKCNA5NPC1 | |
| SCHEMBL13572965 | 0.81 | KCNA5 (0.61) | L3MBTL1KCNA5MEN1NPC1RAB9A | |
| SCHEMBL23685636 | 0.81 | L3MBTL1 (0.59) | L3MBTL1SMN1; SMN2LMNAKCNA5MEN1 | |
| SCHEMBL13573051 | 0.81 | KCNA5 (0.61) | L3MBTL1KCNA5MEN1NPC1RAB9A | |
| SCHEMBL27810911 | 0.81 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2LMNAKCNA5TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187280-A | Dopaminergic, antipsychotic and antihypertensive agents | WARNER-LAMBERT COMPANY (US) | 1993-02-16 | — | — | US | disclosed |