Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467759 | 0.80 | GRIK1 (0.57) | HAO1ALDH1A1LMNASMN1; SMN2HDAC3 | |
| SCHEMBL6904913 | 0.76 | HAO1 (0.39) | HAO1ALDH1A1LMNASMN1; SMN2HDAC3 | |
| SCHEMBL19058802 | 0.74 | MAPT (0.47) | HAO1ALDH1A1LMNASMN1; SMN2HDAC3 | |
| SCHEMBL10492920 | 0.73 | ALDH1A1 (0.59) | HAO1ALDH1A1LMNASMN1; SMN2HDAC3 | |
| SCHEMBL11125910 | 0.73 | ALDH1A1 (0.59) | HAO1ALDH1A1LMNASMN1; SMN2HDAC3 | |
| SCHEMBL7064025 | 0.73 | CYP3A4 (0.59) | ALDH1A1RECQLCYP2C9PAMGRIK1 | |
| SCHEMBL1717110 | 0.73 | CYP3A4 (0.59) | ALDH1A1RECQLCYP2C9PAMGRIK1 | |
| SCHEMBL19872767 | 0.72 | MAPT (0.44) | ALDH1A1LMNASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL18774307 | 0.72 | MAPT (0.44) | HAO1ALDH1A1LMNASMN1; SMN2HDAC3 | |
| Butadiene SCHEMBL3762435 | 0.70 | MAPT (0.50) | HAO1ALDH1A1LMNASMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474589-A1 | Orthophenolacetamides | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |