SCHEMBL9467809

SCHEMBL9467809

COc1cccc(OC)c1C(=O)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.67
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67
CA7 P43166 1/20 0.67
CA9 Q16790 1/20 0.67
CA14 Q9ULX7 1/20 0.67
RAB9A P51151 3/20 0.59
NPC1 O15118 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
MAPT P10636 6/20 0.56
KDM4E B2RXH2 2/20 0.56
HSD17B10 Q99714 2/20 0.56
ALOX15 P16050 1/20 0.56
MAPK1 P28482 1/20 0.56
ATM Q13315 2/20 0.56
LMNA P02545 4/20 0.55
L3MBTL1 Q9Y468 4/20 0.55
HPGD P15428 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27627508 0.91 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8619008 0.89 SLC6A3 (0.57) CA12CA1CA2CA7CA9
SCHEMBL15125784 0.89 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL11740819 0.89 CA1 (0.58) CA12CA1CA2CA7CA9
SCHEMBL27873369 0.87 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL28312260 0.87 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL6306089 0.87 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL4708761 0.87 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL11755425 0.87 CA1 (0.71) CA12CA1CA2CA7CA9
SCHEMBL29851511 0.86 CA12 (0.59) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5185330-A Penicillins/ad/ TOYAMA CHEMICAL CO., LTD. (JP) 1993-02-09 US claimed
EP-0325571-B1 NEW AMINES, THEIR USE AND PREPARATION Kabi Pharmacia AB (SE) 1991-08-07 EP disclosed
EP-0354234-A1 NEW AMINES, THEIR USE AND PREPARATION KabiVitrum AB (SE) 1990-02-14 EP disclosed
WO-1989006644-A1 NEW AMINES, THEIR USE AND PREPARATION KABIVITRUM AB (SE) 1989-07-27 WO disclosed