Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467397 | 0.84 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL3678528 | 0.83 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL9468547 | 0.81 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBPTPN1 | |
| SCHEMBL11344536 | 0.81 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL9468462 | 0.78 | NPC1 (0.39) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL16425822 | 0.77 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL27375828 | 0.76 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL5668000 | 0.76 | PTPN1 (0.50) | NPC1RAB9ALMNAPOLBPTPN1 | |
| SCHEMBL11420200 | 0.75 | HSPA5 (0.43) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL10359244 | 0.74 | NPC1 (0.35) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264406-A | Alkali or alkaline metal hypophosphites with amines | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5264541-A | Nylon 6 synthesis with water, alkali metal hypophoshite catalyst and amine cocatalyst | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5260246-A | Comprising alkali metal/alkaline earth hypophosphites and amine or benzotriazole cocatalysts | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-09 | — | — | US | disclosed |