Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14323123 | 0.88 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBBCL2 | |
| SCHEMBL14323973 | 0.88 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBBCL2 | |
| SCHEMBL31267653 | 0.82 | NPC1 (0.44) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL31079418 | 0.82 | NPC1 (0.44) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL675255 | 0.82 | NPC1 (0.44) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL9467397 | 0.82 | NPC1 (0.44) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL9467893 | 0.81 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBPTPN1 | |
| SCHEMBL2380314 | 0.80 | NPC1 (0.45) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL699155 | 0.80 | NPC1 (0.47) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL14324434 | 0.79 | MEN1 (0.40) | NPC1RAB9APOLBNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264406-A | Alkali or alkaline metal hypophosphites with amines | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5264541-A | Nylon 6 synthesis with water, alkali metal hypophoshite catalyst and amine cocatalyst | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5260246-A | Comprising alkali metal/alkaline earth hypophosphites and amine or benzotriazole cocatalysts | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-09 | — | — | US | disclosed |