Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468462 | 0.88 | NPC1 (0.39) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL9468544 | 0.88 | NPC1 (0.39) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL9467893 | 0.84 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL9468547 | 0.82 | NPC1 (0.40) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL29903 | 0.81 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL29354035 | 0.81 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL6558920 | 0.80 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL1499910 | 0.80 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL7519989 | 0.80 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBPPARG | |
| SCHEMBL30393631 | 0.80 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264406-A | Alkali or alkaline metal hypophosphites with amines | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5264541-A | Nylon 6 synthesis with water, alkali metal hypophoshite catalyst and amine cocatalyst | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-23 | — | — | US | disclosed |
| US-5260246-A | Comprising alkali metal/alkaline earth hypophosphites and amine or benzotriazole cocatalysts | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-11-09 | — | — | US | disclosed |