SCHEMBL9467964

SCHEMBL9467964

CCOC(=O)C(Cc1ccccc1)c1ccc(CC(C)=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.52
EPHX2 P34913 2/20 0.48
PPARG P37231 2/20 0.48
MMP8 P22894 1/20 0.48
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
EPHX1 P07099 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GPR119 Q8TDV5 1/20 0.43
CNR2 P34972 1/20 0.42
POLB P06746 1/20 0.41
UBE2N P61088 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9467959 0.96 CHRM1 (0.53) CHRM1EPHX2PPARGMMP8ESR1
SCHEMBL15553196 0.87 CHRM1 (0.66) CHRM1EPHX2PPARGMMP8ESR1
SCHEMBL7028 0.83 CHRM1 (0.55) CHRM1EPHX2PPARGMMP8ESR1
SCHEMBL8871420 0.80 LMNA (0.64) CHRM1PPARGALDH1A1
SCHEMBL5145508 0.79 ESR1 (0.53) CHRM1ESR1ESR2EPHX1ALDH1A1
SCHEMBL15552300 0.79 LDHA (0.54) CHRM1EPHX2PPARGESR1ESR2
SCHEMBL9194528 0.79 CHRM1 (0.57) CHRM1EPHX2PPARGUBE2N
SCHEMBL14021577 0.78 LMNA (0.62) CHRM1PPARGALDH1A1
SCHEMBL11860076 0.78 ESR1 (0.54) CHRM1EPHX2PPARGESR1ESR2
SCHEMBL9391853 0.77 POLB (0.49) MMP8ALDH1A1CNR2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5232946-A Promoting weight gain and reduction of blood sugar and fat deposits in animals, feed efficiency DR. KARL THOMAE GMBH (DE) 1993-08-03 US disclosed