Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15151195 | 0.98 | TTR (0.50) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL9468242 | 0.96 | TTR (0.48) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL5284994 | 0.86 | TTR (0.60) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL29409575 | 0.85 | TTR (0.61) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL703189 | 0.85 | TTR (0.61) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL7710380 | 0.83 | TTR (0.59) | TTRCYP1A2CTRB1COMTAURKA | |
| Hydrochloric Acid SCHEMBL11157253 | 0.83 | TTR (0.59) | TTRCYP1A2CTRB1COMTAURKA | |
| Benzenesulfonamide SCHEMBL6672452 | 0.80 | TTR (0.50) | TTRCYP1A2AURKAAURKBTSHR | |
| SCHEMBL8028660 | 0.78 | TTR (0.72) | TTRCYP1A2CTRB1COMTAURKA | |
| SCHEMBL1502472 | 0.78 | TTR (0.72) | TTRCYP1A2CTRB1COMTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239052-A | Heating aromatic disulfide in the presence of an aromatic halide | HAY ALLAN S (CA) | 1993-08-24 | — | — | US | disclosed |
| US-5177183-A | Reaction of a halophenyl disulfide to form polyphenylene thioether | HAY ALLAN S (CA) | 1993-01-05 | — | — | US | disclosed |