SCHEMBL9468274

SCHEMBL9468274

Cc1ccccc1OC(=O)CCCC(=O)Oc1ccccc1C

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 1/20 0.54
RECQL P46063 1/20 0.54
KMT2A Q03164 1/20 0.54
MAPT P10636 1/20 0.44
PPARG P37231 1/20 0.44
BCHE P06276 1/20 0.44
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14359740 0.94 TDP1 (0.54) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL16887727 0.93 KDM4E (0.53) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL29941922 0.92 TDP1 (0.58) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL644115 0.92 TDP1 (0.58) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL27544214 0.92 TDP1 (0.52) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL499472 0.91 KMT2A (0.67) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL28372094 0.90 KDM4E (0.53) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL28207073 0.90 TDP1 (0.50) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL8934268 0.90 KDM4E (0.60) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL28718813 0.89 L3MBTL1 (0.54) TDP1ATML3MBTL1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914334-A Polyester copolymer 阿凡田知识中心有限公司 2020-03-24 CN disclosed
US-9081133-B2 Polarizing plate protective film, polarizing plate, and liquid crystal display Konica Minolta, Inc. (JP) 2015-07-14 US disclosed
US-5262313-A Reaction of carrageen with esterase and hardening drops ANDCARE, INC. (US) 1993-11-16 US disclosed