SCHEMBL644115

SCHEMBL644115

Cc1ccccc1OC(=O)CCC(=O)Oc1ccccc1C

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
ATM Q13315 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 1/20 0.49
RECQL P46063 1/20 0.49
KMT2A Q03164 1/20 0.49
PPARG P37231 1/20 0.46
BCHE P06276 1/20 0.46
CYP1A2 P05177 1/20 0.46
TSHR P16473 1/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
NOTUM Q6P988 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941922 1.00 TDP1 (0.58) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL2996036 0.93 ATM (0.53) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL9468274 0.92 TDP1 (0.55) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL14359740 0.90 TDP1 (0.54) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL3079343 0.90 TDP1 (0.54) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL6963269 0.89 TDP1 (0.53) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL24848222 0.88 TDP1 (0.49) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL241599 0.88 TDP1 (0.58) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL30491153 0.87 TDP1 (0.51) TDP1ATML3MBTL1KDM4EMEN1
SCHEMBL499472 0.87 KMT2A (0.67) TDP1ATML3MBTL1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN claimed
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN disclosed
EP-2216312-B1 PROCESS FOR PRODUCING ORGANIC COMPOUND M TECHNIQUE CO LTD (JP) 2019-05-01 EP disclosed
EP-2184109-B1 METHOD FOR PRODUCING NANOPARTICLES BY FORCED ULTRA-THIN FILM ROTARY PROCESSING M TECHNIQUE CO LTD (JP) 2017-08-23 EP disclosed
US-9211510-B2 Method for producing nanoparticles by forced ultrathin film rotary processing M. TECHNIQUE CO., LTD. (JP) 2015-12-15 US disclosed
US-8592498-B2 Method for producing organic compound and organic compound obtained by the method M. TECHNIQUE CO., LTD. (JP) 2013-11-26 US disclosed
US-8318052-B2 Diketopyrrolopyrrole cocrystals with high transparency CLARIANT FINANCE (BVI) LIMITED (VG) 2012-11-27 US disclosed
US-8119042-B2 Diketopyrrolopyrrole cocrystals CLARIANT FINANCE (BVI) LIMITED (VG) 2012-02-21 US disclosed
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD M. TECHNIQUE CO., LTD. (JP) 2011-07-21 US disclosed
US-20100213421-A1 Diketopyrrolopyrrole Cocrystals CLARIANT FINANCE (BVI) LIMITED (VG) 2010-08-26 US disclosed
US-6723138-B2 UTILIZING MATERIAL MADE IN MINIATURIZED CONTINUOUS REACTOR. CLARIANT INTERNATIONAL LTD. (CH) 2004-04-20 US disclosed
US-20030158410-A1 Chemical synthesis of pigment red 254 in a miniaturized continuous reactor; process control by an integrated circuits CLARIANT INTERNATIONAL LTD. (CH) 2003-08-21 US disclosed
US-6566519-B2 Reacting succinic diester with nitrile CLARIANT INTERNATIONAL LTD. (CH) 2003-05-20 US disclosed
US-20020010331-A1 Reacting succinic diester with nitrile CLARIANT GMBH 2002-01-24 US disclosed
US-5492564-A HIGH OPACITY, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1996-02-20 US disclosed
EP-0302516-A2 Optical article made of amorphous thermoplastic polyester resin MITSUBISHI RAYON CO., LTD. (JP) 1989-02-08 EP disclosed
US-4749795-A Phenyl substituted pyrrolinones CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
US-4720305-A Mixtures of pigments CIBA-GEIGY CORPORATION (US) 1988-01-19 US disclosed
US-4681971-A Phenyl substituted aminodicarboxylate esters CIBA-GEIGY CORPORATION (US) 1987-07-21 US disclosed
US-4579949-A REACTING DISUCCINATE WITH NITRILES CIBA-GEIGY CORPORATION (US) 1986-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010331-A1 Reacting succinic diester with nitrile SDHA, QDPR, SDHB TDP1 1570/4885ATM 2989/4885L3MBTL1 4685/4885
US-20110178199-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND ORGANIC COMPOUND OBTAINED BY THE METHOD OR10J3, PORCN, ABCG2 TDP1 1880/4885ATM 454/4885L3MBTL1 4628/4885
US-20030158410-A1 Chemical synthesis of pigment red 254 in a miniaturized continuous reactor; process control by an integrated circuits TYR, PPOX, QDPR TDP1 2996/4885ATM 3223/4885L3MBTL1 4507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.