Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977159 | 0.85 | MAP3K14 (0.38) | MAP3K14CYP19A1LMNAMAPTPKM | |
| SCHEMBL3805680 | 0.84 | MAP3K14 (0.36) | MAP3K14LMNAMAPTPKMMEN1 | |
| SCHEMBL10488014 | 0.82 | MAP3K14 (0.35) | MAP3K14LMNAMAPTPKMMEN1 | |
| SCHEMBL1332286 | 0.82 | NPC1 (0.36) | MAP3K14CYP19A1LMNAMAPTPKM | |
| SCHEMBL11095324 | 0.82 | NPC1 (0.36) | MAP3K14CYP19A1LMNAMAPTPKM | |
| SCHEMBL1273192 | 0.82 | MAP3K14 (0.35) | MAP3K14LMNAMAPTPKMMEN1 | |
| SCHEMBL13386960 | 0.81 | MAP3K14 (0.32) | MAP3K14 | |
| SCHEMBL20589363 | 0.81 | PRKCA (0.38) | MAP3K14CYP19A1LMNAMAPTPKM | |
| SCHEMBL6551912 | 0.79 | HSD17B10 (0.39) | CYP19A1 | |
| SCHEMBL7264550 | 0.77 | MAP3K14 (0.40) | MAP3K14CYP19A1LMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262035-A | Polymer and enzyme | E. HELLER AND COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| WO-1992012254-A1 | ENZYME ELECTRODES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-07-23 | — | — | WO | disclosed |