SCHEMBL977159

SCHEMBL977159

O=C1CC(OC(=O)CCC(=O)OC2CC(=O)NC2=O)C(=O)N1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.38
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
MEN1 O00255 1/20 0.33
APEX1 P27695 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CRBN Q96SW2 7/20 0.31
DDB1 Q16531 6/20 0.31
NPC1 O15118 1/20 0.31
MMP3 P08254 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ITGB3 P05106 1/20 0.31
ITGB2 P05107 1/20 0.31
ITGB1 P05556 1/20 0.31
ITGAV P06756 1/20 0.31
ITGA2B P08514 1/20 0.31
ITGA5 P08648 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20589363 0.91 PRKCA (0.38) MAP3K14LMNAMAPTPKMMEN1
SCHEMBL6551912 0.90 HSD17B10 (0.39) NPC1CYP19A1
SCHEMBL13386960 0.88 MAP3K14 (0.32) MAP3K14
SCHEMBL3805680 0.87 MAP3K14 (0.36) MAP3K14LMNAMAPTPKMMEN1
SCHEMBL9682839 0.85 PRKCA (0.33) MAP3K14LMNAMAPTPKMMEN1
SCHEMBL17941727 0.85 NLRP3 (0.39) MAP3K14
SCHEMBL1273192 0.85 MAP3K14 (0.35) MAP3K14LMNAMAPTPKMMEN1
SCHEMBL10488014 0.85 MAP3K14 (0.35) MAP3K14LMNAMAPTPKMMEN1
SCHEMBL11095324 0.85 NPC1 (0.36) MAP3K14LMNAMAPTPKMMEN1
SCHEMBL9468465 0.85 MAP3K14 (0.35) MAP3K14LMNAMAPTPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791591-A Insulin aspart, insulin aspart compound and preparation method and application thereof 浙江大学 2024-10-18 CN claimed
CN-118791591-A Insulin aspart, insulin aspart compound and preparation method and application thereof 浙江大学 2024-10-18 CN disclosed
US-8435614-B2 Low temperature molding process for making solid biodegradable articles GREEN MATERIALS, LLC (US) 2013-05-07 US disclosed
US-20110223367-A1 LOW TEMPERATURE MOLDING PROCESS FOR MAKING SOLID BIODEGRADABLE ARTICLES R&D GREEN MATERIALS, LLC (US) 2011-09-15 US disclosed
US-7867587-B2 Low temperature molding process for making solid biodegradable articles R&D GREEN MATERIALS, LLC (US) 2011-01-11 US disclosed
EP-1778461-A2 LOW TEMPERATURE MOLDING PROCESS FOR MAKING SOLID BIODEGRADABLE ARTICLES R&D Green Materials, LLC (US) 2007-05-02 EP disclosed
WO-2006017481-A2 LOW TEMPERATURE MOLDING PROCESS FOR MAKING SOLID BIODEGRADABLE ARTICLES R & D GREEN MATERIALS, LLC (US) 2006-02-16 WO disclosed
US-20060027941-A1 Low temperature molding process for making solid biodegradable articles R&D GREEN MATERIALS, LLC (US) 2006-02-09 US disclosed
US-6045868-A Method for the preparation of transparent cross-linked polymers from grain flour BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2000-04-04 US disclosed